Prevalence of rhesus type and abo incompatibility in jaundiced neonates

To determine the prevalence of Rh and ABO incompatibility in jaundiced neonates. This hospital based descriptive study was conducted in Pediatrics Unit, Lady Reading Hospital Peshawar. A total of 200 neonates with clinically diagnosed jaundice were included in the study. Out of 200 neonates 70% were male and 30%female. Majority of neonates 99.5% age was ranged from 0-10 days while only 0.5% neonate was 13 days. Out of 200 neonates, the frequency of ABO-incompatibility and Rh-incompatibility in jaundiced neonates in this study was 22.5% and 12.5% respectively. Out of the remaining 65.5% cases physiological jaundice was diagnosed in 40.5% neonates, prematurity in 15% neonates and G6PD in 9.5% neonates. Among 22.5% cases of ABO incompatibility there were 16.5% males and 6% females. Majority 15% presented on 1[st] day of life, followed by 3% on 2[nd] and 3[rd] day of life respectively, 1% on 4[th] day, 0.5% on 5[th] day of life. Out of 200 neonates presented with jaundice, prevalence of ABO-incompatibility was found to be 22.5% followed by Rh-incompatibility 12.5%

Frecuencias de grupos sanguíneos e incompatibilidades ABO y RhD, en La Paz, Baja California Sur, México / Blood group frequencies and ABO and RhD incompatibilities in La Paz, Baja California Sur, Mexico

OBJECTIVE: To determine genic and phenotypic frequencies and predict the risk of incompatibility and maternal alloimmunization in the population of La Paz. MATERIAL AND METHODS: This descriptive study evaluated 1809 voluntary blood donors attending in 1998 the Hospital General de Zona of Instituto Mexicano del Seguro Social (Zone General Hospital of the Mexican Institute of Social Security) in La Paz, Baja California Sur, Mexico. Blood donors were typified by tube agglutination. The gene frequencies were estimated assuming equilibrium conditions, and incompatibilities and alloimmunization were statistically assessed with the chi 2 test. RESULTS: Percent frequencies were as follows: blood group O, 58.49; A, 31.40; B, 8.40; AB, 1.71; RhD, 95.36; and RhD negative, 4.64. Genic frequencies were: i, 0.7648; IA, 0.1821; IB, 0.0519; D, 0.7845; and d, 0.2155, respectively. Incompatibilities between couples and mother-child were 0.3023 and 0.1685 for ABO, 0.0442 and 0.0364 for RhD, and 0.0134 and 0.0061 for double incompatibility, respectively. The probability of maternal alloimmunization was estimated at 0.0309. CONCLUSIONS: The O and RhD groups were the most common in La Paz, although frequencies were among the lowest in Mexico, contrary to the case of A and RhD negative groups. The probabilities of maternal alloimmunization and of incompatibilities were also high. Ancestral white, black, and indigenous groups admixed in the northwestern part of Mexico; after migrating to Baja California Sur the admixture of the population probably became similar to that of the remainder of the northwestern area.

Evoluçäo clínica e laboratorial de crianças ictéricas com possibilidade de incompatibilidade sanguínea materno-fetal pelo sistema ABO, nascidas no Hospital das Clínicas de Ribeiräo Preto / Clinical and laboratorial course in children with jaundice with of maternal-fetal blood incompatibility by ABO system, born at the Hospital das Clínicas of Ribeiräo Preto

O presente estudo apresenta a evoluçäo clínica e laboratorial de crianças nascidas no Hospital das Clínicas da Faculdade de Medicina de Ribeiräo Preto (HCFMRP) com possibilidade de isoimunizaçäo materno-fetal pelo sistema ABO. Foram incluídas no trabalho 87 crianças que apresentaram icterícia, foram submetidas a fototerapia e tiveram seguimento ambulatorial completo. Estas crianças provieram de um total de 480 nascimentos ocorridos no ano de 1983 em que as mäes eram do tipo O e os recém-nascidos do tipo A ou B. Foram estudados as condiçöes de nascimento, os valores preditivos do teste de Coombs direto do sangue do cordäo, da pesquisa de hemolisina no sangue materno e do tempo de aparecimento da icterícia no diagnóstico da gravidade do quadro e a evoluçäo ambulatorial. As condiçöes de nascimento das crianças participantes do estudo foram semelhantes às do grupo-controle e da populaçäo geral. A maior gravidade do quadro näo foi associada a nenhum dos parâmetros testados (Coombs direto positivo, pesquisa de hemolisina positiva, icterícia precoce e tipo sangüíneo da criança A ou B). O seguimento das crianças demonstrou ser desnecessário o acompanhamento sistemático de seus níveis de hemoglobina. Conlui-se que o manejo das crianças com possibilidade de incompatibilidade ABO näo deve diferir do de outras crianças ictéricas. A monitoragem contínua e cuidadosa da bilirrubina plasmática nestas crianças tem mostrado ser o único meio prático de indicar a gravidade do caso

Los grupos sanguíneos ABO y Rh (D) en poblaciones de la Región Lagunera de México (Calculo de la frecuencia de incompatibilidad simple y doble en matrimónios y maternofetal) / ABO and Rh (D) blood groups in populations of the Laguna Region, Mexico. Estimate of simple and double incompatibility frequency in married subjects and maternal-fetal

Se determinaron los grupos sanguíneos de los sistemas ABO y Rh(D) en 9.351 personas que acudían a diferentes centros médicos de las ciudades de Torreon, Coahuila y Gomez Palacio, Durango en la Región Lagunera México; encontrándose los porcentajes siguientes para ABO: A, 26,37; B, 9,70; AB, 1,87; O, 62,06, y para Rh(D): Rh(D) +, 95,86 y Rh(D)-, 4,14. Con base en estas frecuencias se estimaron los porcentajes de matrimonios incompatibles siendo de 29,34 por ABO, 3,97 por Rh(D) y de 1,16 para ambos, y los porcentajes de incompatibilidad maternofetal siendo de 16,22 por ABO, 3,31 por Rh(D) y 0,54 para ambos. Se encontró que las frecuencias anteriores tanto de grupos sanguíneos como de incompatibilidad, eran intermedias a las informadas para poblaciones antecesoras, indígenas, mexicanos y españoles, y similares a lo encontrado en poblaciones mestizas del estado de Nuevo Leon, México